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MDRD GFR Equation
Estimates Glomerular Filtration Rate (GFR) in patients with stable Chronic Kidney Disease (CKD).
Sex
Biological sex of the patient
Age
Patient’s age in years
Creatinine
Serum creatinine level (mg/dL)
Black Race
Optional; may provide better estimates
0
mL/min/1.73m²
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CKD Classification (Estimated)
| Stage | GFR Range | Description |
|---|---|---|
| Stage 1 | ≥ 90 | Normal or High |
| Stage 2 | 60 – 89 | Mildly Decreased |
| Stage 3a | 45 – 59 | Mild to Moderate Decrease |
| Stage 3b | 30 – 44 | Moderate to Severe Decrease |
| Stage 4 | 15 – 29 | Severely Decreased |
| Stage 5 | < 15 | Kidney Failure |
1
Not for Acute Failure: MDRD is only accurate for stable Chronic Kidney Disease (CKD). It should not be used in Acute Renal Failure (ARF).
2
High GFR Bias: This equation tends to underestimate GFR significantly when the value is >60 ml/min/m².
3
Medication Adjustment: Medications should be dose-adjusted based on the most recent eGFR, especially cutoffs at <60, <45, and <30.
